The purpose of this research are to analyze the influence of container crane productivity (X1) and ship call frequency (X2) on the number of containers handled (Y) at Semarang Container Terminal branch PT. Pelabuhan Indonesia III. The tool of analysis which was used was Multiple Regression with Classic Assumption Test. This research used secondary data obtained from TPKS such as monthly report the achievement of performance, monthly report of ship call and monthly report of stevedoring production within period of 6.5 years (January 2009 – June 2015). The Result of the Multiple Regression Analysis was LogY = 4.923991 + 0.525387 log XI + 0.423276 log X2 + e. This equation showed that all regression coefficients were positive. It means that if container crane productivity and ship call frequency was increased, the number of the containers handled would increase too. β1 = 0.525, it means that if there is increase in container crane productivity by 10%, it will increase the cargo handling performance by 5.25%. Next, β2 = 0.423, it explains that if there is an increase in ship call frequency by 10%, it will increase the cargo handling performance by 4.23%. The result of Coefficient of Determination of Test shows that container crane productivity and ship call frequency give the proportion or percentage of the total variation in the number of containers handled for about 94,8%. While, F-Test shows that container crane productivity and ship call frequency influenced simultaneously on the number of containers handled. Furthermore, container crane productivity influenced positively on the number of containers handled. Then the other X variable, ship call frequency influenced positively on the number of containers handled.