Office space arrangement is important to succeed the company, and Administration division of Balai Besar Teknologi Pencegahan Pencemaran Industri Semarang has function to seek the services of research, therefore the Administration division needs office space arrangement to improve the employees performance efficiency. The objective of this report is to examine the arrangement of equipment and office supplies of the administration section at Balai Besar Teknologi Pencegahan Pencemaran Industri Semarang and to provide an alternative arrangement of the office lay out to improve the work efficiency of employees. This final project used descriptive analysis method. The data were collected by conducting observation, interviews, questionnaires and literature review. This research shows that the office lay out in the Administration section of Balai Besar Teknologi Pencegahan Pencemaran Industri Semarang is an open office layout. It enabled the employees to communication, and saves a limited area of the room. Spatial arrangement of the administration office was still not good enough, for instance: there were two empty spaces which were not used, mobility work flow was not efficient, placement of attendance machine in administration section room could disturb the concentration of employees’, and the bulk of documents below and above the table created the impression of untidiness. Therefore, it could not increase the employees job efficiency. In order to create neat impression inside the room and to improve working efficiency, both type officer and verificator of test results should be placed in a typingroom to decrease mobility frequency. In addition, the office should exploit all the existing space and moving the attendance machine on the ground floor in order to hinder many distrubance of employees activities and finally it was important to keep active documents in the filing cabinets.